Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications
AssigneeCase Western Reserve University
InventorsNicole F. Steinmetz, Paul L. Chariou
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Abstract
An agricultural composition includes a plurality of rod-shaped plant viral nanoparticles (VNPs) and/or virus-like particles (VLPs), each VNP and/or VLP having an exterior surface and an interior surface that extend from a first end to a second of the rod-shaped VNP and/or VLP, the interior surface defining a channel that extends through rod-shaped VNP from the first end to the second end; and at least one agrochemical agent attached or conjugated to the interior and/or exterior surface of the rod-shaped plant VNPs and/or VLPs.
Claims9
A method of treating a plant, comprising applying an agricultural composition to the plant in a treatment effective amount to combat nematode parasitism on the plant, the agricultural composition including a plurality of tobacco mild green mosaic virus (TMGMV) and/or VLPs thereof, each TMGMV and/or VLP having an interior surface that extends from a first end to a second end of the TMGMV and/or VLP, the interior surface defining a channel that extends through TMGMV and/or VLPs thereof from the first end to the second end;
- and crystal violet (hexamethyl parparosaniline chloride) non-covalently loaded onto negatively charged interior surface of the TMGMV and/or VLPs by electrostatic interactions, wherein the negatively charged interior surface of the TMGMV and/or VLPs thereof includes a solvent exposed glutamic acid 95 (Glu95) amino acid residue on the interior surface of the TMGMV and/or VLPs thereof.
Dependencies are inferred from the claim text.