Method for generating photographed image data using virtual organoid
AssigneeNext & Bio Inc.
InventorsJi Hun Yang, Eui Jeong Song, Tae Hwan Kwak, Si Young Lee
Life of this patent
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Abstract
A method for generating a virtual organoid having various shapes and characteristics; and a virtual organoid photographing method which can achieve the same effect as that of image data obtained by photographing a real organoid. The method for generating a virtual organoid according to the present specification may generate data about an organoid structure in a virtual space to reflect the characteristics of a real organoid. The photographing method using a virtual organoid according to the present specification may generate image data which can achieve the same effect as that achieved when photographing a real organoid.
Claims7
A method for generating photographed image data using a virtual organoid generated in a virtual three-dimensional space comprising:
- performed by a processor,
- (a) setting a position of a light source in the virtual three-dimensional space,
- (b) setting a focal plane in the virtual three-dimensional space,
- (c) calculating a brightness and a clarity of each cell in the virtual organoid by considering the position of the light source and a position of the focal plane;
- and
- (d) generating the photographed image data of the virtual organoid to which the calculated brightness and clarity of the cell are reflected,
- wherein the virtual organoid is generated by the processor which
- generates a random positive number and generating unit ellipsoids having same size and same parameters as many as the generated random number;
- places a center point of the each unit ellipsoids generated in the step (a) by setting an arbitrary coordinate in a three-dimensional space;
- generates cavity ellipsoids having the same parameters as the unit ellipsoid in which the center point of each cavity ellipsoid is present in the corresponding unit ellipsoid as many as the number of the unit ellipsoids;
- generates mass data by removing a set of the cavity ellipsoids from a set of the unit ellipsoids;
- converts the mass data into voxel data according to a predetermined resolution;
- and
- randomly places organoid cells in the voxel data.
A device for generating photographed image data using a virtual organoid generated in a virtual three-dimensional space comprising:
- a processor which sets a position of a light source in a virtual three-dimensional space, sets a focal plane in the virtual three-dimensional space, calculates a brightness and a clarity of each cell in the virtual organoid by considering the position of the light source and a position of the focal plane;
- and generates the photographed image data of the virtual organoid to which the calculated brightness and clarity of the cell are reflected,
- wherein the virtual organoid is generated by the processor which
- generates a random positive number and generating unit ellipsoids having same size and same parameters as many as the generated random number;
- places a center point of the each unit ellipsoids generated in the step (a) by setting an arbitrary coordinate in a three-dimensional space;
- generates cavity ellipsoids having the same parameters as the unit ellipsoid in which the center point of each cavity ellipsoid is present in the corresponding unit ellipsoid as many as the number of the unit ellipsoids;
- generates mass data by removing a set of the cavity ellipsoids from a set of the unit ellipsoids;
- converts the mass data into voxel data according to a predetermined resolution;
- and
- randomly places organoid cells in the voxel data.
Dependencies are inferred from the claim text.