Systems and methods for updating a graphical user interface based upon intraoperative imaging

A system comprising:

• one or more processors;
• a user display;
• and
• memory having computer readable instructions stored thereon, wherein the computer readable instructions, when executed by the one or more processors, cause the system to:
• obtain pre-operative image data of anatomical passages of a patient, wherein the pre-operative image data includes a target lesion;
• display, in a graphical user interface on the user display, a model of the anatomical passages of the patient and the target lesion, wherein the model is generated from the pre-operative image data;
• receive intra-operative image data from an imaging system;
• instruct a user to identify the target lesion in the intra-operative image data;
• receive a user selection of a portion of the intra-operative image data corresponding to the target lesion;
• based on the user selection, determine a location of the target lesion from the intra-operative image data;
• instruct a user to identify a portion of the intra-operative image data corresponding to an instrument disposed in the anatomical passages of the patient;
• receive a user selection of the portion of the intra-operative image data corresponding to the instrument;
• display, on the user display, a boundary overlaid on the intra-operative image data, the boundary corresponding to a portion of the instrument visible in the intra-operative image data;
• register an intra-operative image reference frame of the intra-operative image data to an instrument reference frame of the instrument;
• map the location of the target lesion from the intra-operative image data to the instrument reference frame;
• update a location of the target lesion in the model to the location of the target lesion from the intra-operative image data;
• and
• display, in the graphical user interface on the user display, the model with the updated location of the target lesion.