# US 12,595,455 B2 · Screen changing device, and system and method of reducing the size of living tissue in using the same

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- Number: US 12,595,455 B2
- Document ID: US12595455B2
- Status: Granted
- Kind: B2
- Application number: 18/013,283
- Filed: 2022-10-21
- Published: 2024-02-01
- Granted: 2026-04-07
- Earliest claimed: 2021-10-22
- Applicants: Jun Seok Lee
- Inventors: Jun Seok Lee
- Web page: https://patentgrep.com/patent/US12595455B2

## CPC

- C12M 23/10: {Petri dish (crystallising dishes B01L3/06)}
- C12M 33/04: {by injection or suction, e.g. using pipettes, syringes, needles (pipettes in general B01L3/02)}
- A61L 27/36: containing ingredients of undetermined constitution or reaction products thereof {, e.g. transplant tissue, natural bone, extracellular matrix (isolated natural compounds, e.g. collagen A61L27/24)}
- A61M 1/00: Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems (catheters A61M25/00; tube connectors, tube couplings, valves or branch units specially adapted for medical use A61M39/00; devices for taking samples of blood A61B5/15; filters implantable into blood vessels A61F2/01)
- B02C 19/00: Other disintegrating devices or methods (for grain B02C9/00)
- C12M 23/12: {Well or multiwell plates (C12M25/04 takes precedence)}
- C12M 23/50: {Means for positioning or orientating the apparatus (C12M41/08 takes precedence)}
- C12M 25/04: {in combination with well or multiwell plates, i.e. culture inserts}
- C12M 33/12: {by pressure}
- C12M 33/14: {with filters, sieves or membranes}
- A61J 1/2058: {having multiple connecting ports}
- C12M: APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; {APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS}
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- B02C: CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN ({household tools and machines for pulverising foodstuffs, e.g. coffee and spice mills A47J42/00; pharmaceutical mortars A61J3/02; mechanical processing of refuse and garbage B03B9/06; dressing mould materials by grinding B22C5/04}; obtaining metallic powder by crushing, grinding or milling B22F9/04; {recovery of plastics by disintegrating B29B17/00; crushing raw materials in starch making C08B30/02; beaters for papermaking D21D1/02; crushing devices specially for transport in mines E21F13/002; slag crushing devices F23J1/00; fuel milling devices in combustion apparatus F23K1/00; household devices for crushing coal F24B15/02; ice disintegrating devices F25C5/02})
- A61J: CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE

## Abstract

A screen changing device is proposed. The screen changing device includes a first housing and a second housing configured to be rotated with respect to the first housing. The screen changing device can transit from a first configuration in which a first screen is aligned with a first connector and a second connector to a second configuration in which the first screen is not aligned with the first connector and the second connector and a second screen is aligned with the first connector and the second connector.

## Claims

### Claim 1

A screen changing device comprising:
a first housing comprising
a first base,
an outer wall connected to the first base,
an inner wall connected to the first base and being opposite to the outer wall,
a first space defined between the outer wall and the inner wall,
a second space defined by the inner wall,
a first connector disposed on the outer wall, and
a second connector disposed on the inner wall and in the second space;
a second housing comprising
a second base,
a supporting wall connected to the second base and disposed in the first space, and
a plurality of recesses arranged in a circumferential direction of the supporting wall; and
a plurality of screens disposed in the plurality of recesses, respectively, and configured to reduce a size of a living tissue,
a body cap disposed between the inner wall and the second base,
wherein the second housing is configured to be rotated with respect to the first housing from a first configuration, in the first configuration, a first screen of the plurality of screens is aligned with the first connector and the second connector to a second configuration, in the second configuration, the first screen is not aligned with the first connector and the second connector and a second screen of the plurality of screens is aligned with the first connector and the second connector.

### Claim 2 (depends on 1)

The screen changing device of claim 1, further comprising a plurality of caps configured to retain the first screen, wherein the first screen corresponds to a first recess of the plurality of recesses, and the first screen of the plurality of screens is in the first recess.

### Claim 3 (depends on 2)

The screen changing device of claim 2, further comprising a first sealing disposed between the plurality of caps and the outer wall.

### Claim 4 (depends on 2)

The screen changing device of claim 2, further comprising a second sealing disposed between the supporting wall and the plurality of caps.

### Claim 5 (depends on 1)

The screen changing device of claim 1, further comprising a third sealing disposed between the supporting wall and the inner wall.

### Claim 6 (depends on 1)

The screen changing device of claim 1, wherein the first connector comprises:
a first protrusion protruding from the outer wall away from a rotation axis; and
a first passage defined in the first protrusion.

### Claim 7 (depends on 1)

The screen changing device of claim 1, wherein the second connector comprises:
a second protrusion protruding from the inner wall; and
a second passage defined in the second protrusion,
wherein the second protrusion comprises:
a first extension extending from the inner wall toward a rotation axis; and
a second extension extending from the first extension in an axial direction of the rotation axis.

### Claim 8 (depends on 1)

The screen changing device of claim 1, further comprising:
a guide groove disposed in the first housing;
a ball disposed in the second housing; and
an elastic member disposed between the guide groove and the ball,
wherein the ball and the elastic member are configured to determine a position of the second housing with respect to the first housing.

### Claim 9 (depends on 1)

The screen changing device of claim 1, wherein the first housing further comprises:
a third connector disposed on the outer wall; and
a fourth connector disposed on the inner wall and in the second space.

### Claim 10 (depends on 1)

The screen changing device of claim 1, further comprising a channel adapter configured to be coupled to the second connector.

### Claim 11 (depends on 1)

The screen changing device of claim 1, further comprising
an indicator showing a rotation direction of the second housing.

### Claim 12 (depends on 1)

The screen changing device of claim 1, wherein the first screen comprises a first through-hole having a first shape, and the second screen comprises a second through-hole having a second shape different from the first shape.

### Claim 13 (depends on 1)

The screen changing device of claim 1, wherein each of the plurality of screens comprises:
a plate; and
a through-hole formed through a front and a rear of the plate and defined by a plurality of edges of the plate,
the plurality of edges each comprises a protrusion protruding toward a center portion of the through-hole, and
while the living tissue pressurized in an internal space of a first syringe and an internal space of a second syringe flows through the through-hole of the each of the plurality of screens disposed in a channel, the plurality of edges and the protrusion of each of the plurality of edges pressurize the living tissue passing through the through-hole and the plurality of edges and the protrusion of each of the plurality of edges scratch and tear the living tissue.

### Claim 14 (depends on 13)

The screen changing device of claim 13, wherein:
in the first configuration, when a first plunger of the first syringe pressurizes an internal space of a first container, the living tissue in the first syringe is moved into the second syringe sequentially through a first passage, the aligned screen, and a second passage; and
in the second configuration, when a second plunger of the second syringe pressurizes an internal space of a second container, the living tissue in the second syringe is moved into the first syringe sequentially through the second passage, the aligned screen, and the first passage.