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AssigneeSichuan Creation Pharmaceutical Technology Co., Ltd.
InventorsLiang Ma, Ping Fu
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The present disclosure relates to the field of medicaments, and particularly to use of Liriodendron chinense (Hemsl.) Sarg, or an extract thereof in the preparation of a medicament for reducing a serum uric acid level and preventing and treating uric acid nephropathy, and belongs to the field of medicaments. In one aspect, the present disclosure provides use of Liriodendron chinense (Hemsl.) Sarg. or an extract thereof in the preparation of a medicament for reducing a serum uric acid level. In another aspect, the present disclosure further provides use of Liriodendron chinense (Hemsl.) Sarg. or an extract thereof in the preparation of a medicament for treating and/or preventing uric acid nephropathy.
A method for reducing a serum uric acid level or for treating or preventing uric acid nephropathy, comprising administering a subject in need thereof an extract of Liriodendron chinense (Hemsl.) Sarg (over 500 mg/kg/d) to relieve a degree of renal interstitial fibrosis of hyperuricemia or to inhibit the expression of α-SMA and to promote renal uric acid excretion, wherein the extract is prepared by adding Liriodendron chinense (Hemsl.) Sarg. into 75% v/v alcohol for extraction.
Dependencies are inferred from the claim text.