# US 12,594,299 B2 · Photosynthetic cellular substances and methods of use thereof

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- Number: US 12,594,299 B2
- Document ID: US12594299B2
- Status: Granted
- Kind: B2
- Application number: 17/891,447
- Filed: 2022-08-19
- Published: 2022-12-15
- Granted: 2026-04-07
- Earliest claimed: 2014-09-03
- Assignees: Symbiox, Inc.
- Applicants: Symbiox, Inc.
- Inventors: Jose-Tomas Egana-Erazo
- Web page: https://patentgrep.com/patent/US12594299B2

## CPC

- A61K 33/00: Medicinal preparations containing inorganic active ingredients
- A61N 5/0616: {Skin treatment other than tanning}
- A61N 2005/0651: {Diodes}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

Systems and methods for developing and applying photosynthetic cellular substances to a human or animal for medical, therapeutic or cosmetic uses are provided. Photosynthetic cells, such as algal cells, can be used in these substances to provide the ability to continuously generate oxygen when exposed to a light source or other oxygen-generating trigger. The substances can be developed as a standalone liquid, gel or cream, or embedded within a bandage, mesh, scaffold or other structure with a light source to promote oxygen production. The substances can be applied topically for medical, therapeutic or cosmetic treatments, or injected internally for generation of oxygen within one or more parts of the body.

## Claims

### Claim 1

A device, comprising:
an application suitable to sit on the surface of skin or another site within mammalian tissues including an absorbent material and embedded with photosynthetic cellular structures, wherein the photosynthetic cellular structures are capable of existing alongside or within mammalian tissues without triggering an immune response; and
a light source embedded within the application configured to provide a certain intensity and pattern of light to the photosynthetic cellular structures, wherein the light source is configured to produce wavelengths in the range of 380 nm to 780 nm, and wherein the photosynthetic cellular structures within the device generate oxygen when exposed to the light at the surface of the skin or exposed tissue to promote the health of the tissue or promote the healing of a wound or other exposed tissue.

### Claim 2 (depends on 1)

The device of claim 1, wherein the photosynthetic cellular structures produce oxygen to help promote the healing of the wound.

### Claim 3 (depends on 1)

The device of claim 1, wherein the device is suitable for use as a chemotherapy treatment for skin cancer.

### Claim 4 (depends on 1)

The device of claim 1, wherein the device further comprises a container fit with one or more light sources to illuminate the interior space of the container, and wherein the container is suitable for use in keeping living tissue alive during storage and before implantation.

### Claim 5 (depends on 1)

The device of claim 1, wherein the device is suitable for use during radiation therapy to increase the effectiveness of radiation in destroying a tumor.

### Claim 6 (depends on 1)

The device of claim 1, wherein the light source is configured to deliver light in a pattern where the light is alternatingly on for a first period, then off for a second period.

### Claim 7 (depends on 1)

The device of claim 1, wherein the absorbent material is a mesh or pad.

### Claim 8 (depends on 1)

The device of claim 1, wherein the photosynthetic cellular structures comprise at least one of algal cells, photosynthetic bacteria, and isolated chloroplasts.