Composition comprising hyaluronic acid and pluronic for preventing or treating articular and cartilage injury
AssigneeMedicrinia, Co., Ltd.
InventorYoo Jin Ha
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AssigneeMedicrinia, Co., Ltd.
InventorYoo Jin Ha
Estimating the term…
The present invention relates to a hydrogel composition prepared without using a binder. The composition is easy to inject into the human body and has a therapeutic effect on intraarticular lesions and inflammation. The hydrogel of the present invention, which is prepared without a binder, is degraded in an articulation for a long time due to the increased viscoelasticity thereof, thereby enjoying the advantage that the absorption time is prolonged. Therefore, when the hydrogel is used as an injection, its efficacy may be maintained for a long time. Furthermore, the hydrogel has no cytotoxicity, thus showing very high biocompatibility. Particularly when directly injected to an injured site in an articulation, the hydrogel has a therapeutic effect on the intraarticular lesion and inflammation in the corresponding site and thus may be advantageously utilized as a composition for prevention or treatment of an intraarticular lesion and as a viscosity supplement.
A method for treatment of an intraarticular lesion, the method comprising administering a hydrogel composition for the prevention or treatment of the intraarticular lesion to a subject, wherein the composition comprises 4 to 9 w/v % of hyaluronic acid and 9 to 11 w/v % of poloxamer.
Dependencies are inferred from the claim text.