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US 12,594,291 B2Granted
Intratumoral alpha-emitter radiation and activation of cytoplasmatic sensors for intracellular pathogen
AssigneeAlpha Tau Medical Ltd.
InventorsVered Domankevich, Yona Keisari, Itzhak Kelson
Life of this patent
Estimating the term…
Abstract
A method of treating a patient with a tumor, and kits (200) for such treatment. The method includes administering, to the patient, a substance (204) which activates cytoplasmatic sensors for intracellular pathogen in the tumor and treating the tumor with intra-tumoral alpha-emitter radiotherapy within two weeks of administering the substance which activates cytoplasmatic sensors for intracellular pathogen in the tumor.
Claims63
A method of treating a patient with a tumor, comprising:
- administering, to the patient, a substance including a pathogen mimic with a delivery agent suitable for cytoplasmic delivery of the pathogen mimic;
- and
- treating the tumor with intra-tumoral alpha-emitter radiotherapy within two weeks of administering the substance.
Dependencies are inferred from the claim text.