Compositions and methods for protecting against airborne pathogens and irritants
AssigneeApplied Biological Laboratories, Inc.
InventorNazlie Latefi
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Abstract
The present disclosure features methods and compositions for enhancing the ability of the respiratory membranes to filter airborne pathogens and protect a subject from respiratory infections that result from inhalation or ingestion of such pathogens. In particular, the disclosure provides antimicrobial compositions that prevent and treat respiratory infections caused by bacteria, fungi, and viruses.
Claims8
A method of protecting the epithelial and mucous membranes of a subject from viral respiratory infection comprising administration of a pharmaceutical composition to the subject having a residence time on the oral mucosa of at least 5 minutes, wherein said pharmaceutical composition comprises a pharmaceutically acceptable carrier and:
- a) lysozyme;
- and
- b) lactoferrin,
- the pharmaceutical composition is in the form of a nasal spray, oral spray, oral rinse, or lozenge, and said composition is isotonic to the nasal epithelia or mucous membrane;
- wherein administration of the pharmaceutical composition to the subject inhibits the viral respiratory infection on the epithelial and/or mucous membranes,
- a weight ratio of lactoferrin:lysozyme of about 1:4 to about 1:25.
Dependencies are inferred from the claim text.