# US 12,594,247 B2 · Edged cataplasm and manufacturing process

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- Number: US 12,594,247 B2
- Document ID: US12594247B2
- Status: Granted
- Kind: B2
- Application number: 18/106,501
- Filed: 2023-02-07
- Published: 2024-05-30
- Granted: 2026-04-07
- Earliest claimed: 2022-11-24
- Assignees: Planet (Anhui) Pharmaceutical Co., Ltd.
- Applicants: Planet (Anhui) Pharmaceutical Co., Ltd.
- Inventors: Xiaoshen Zhou; Yunqiang Ying; Yuan Zhu
- Web page: https://patentgrep.com/patent/US12594247B2

## CPC

- A61K 9/70: Web, sheet or filament bases {; Films; Fibres of the matrix type containing drug (hollow drug-filled fibres A61K9/0092)}
- A61K 9/7084: {Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches}
- A61F 13/00063: {comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic (drug delivery dressings A61K9/70; chemical aspect of the additives A61L15/00)}
- A61F 13/023: {wound covering film layers without a fluid retention layer}
- A61F 13/0253: {characterized by the adhesive material}
- A61F 13/0259: {characterised by the release liner covering the skin adhering layer}
- A61K 47/02: Inorganic compounds
- A61K 47/32: Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers {, poly(meth)acrylates, or polyvinyl pyrrolidone}
- A61K 47/34: Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers (A61K47/10 takes precedence)
- A61L 15/44: Medicaments
- A61L 15/58: Adhesives
- A61L 2300/406: Antibiotics
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

An edged cataplasm and a manufacturing process are disclosed. The edged cataplasm includes a support layer; a drug layer, which adheres to the bottom of the support layer; a cross-type release film, which adheres to the bottom of the drug layer. The cross-type release film includes a first-release film piece and a second-release film piece, and the adjacent edges of the first-release film piece and the second-release film piece are partially overlapped. In addition, the edged cataplasm further includes a waterproof-breathable adhesive layer, which adheres to the top of the support layer and coated with silver ions or a nano antibiotic layer; a polyethylene terephthalate (PET) film, which adheres to the top of the waterproof-breathable adhesive layer. The PET film includes a first part and a second part, and the adjacent edges of the first part and the second part are arranged as an aligned S-shaped edge.

## Claims

### Claim 1

An edged cataplasm, comprising the following layers arranged sequentially from top to bottom:
a polyethylene terephthalate (PET) film comprising a first part and a second part,
a waterproof-breathable adhesive layer,
an antibiotic layer,
a support layer,
a drug layer, and
a release film; wherein
the PET film adheres to the top of the waterproof-breathable adhesive layer;
the waterproof-breathable adhesive layer is a polyurethane (PU) film having a waterproof-breathable property and an adhesive property;
the antibiotic layer comprises silver ions or a nano antibiotic;
the support layer is a polyethylene (PE) mesh film;
silicone oil is coated on the support layer and the drug layer is compounded onto the support layer to form a composite film, and the drug layer is a drug-containing hydrogel, wherein the drug-containing hydrogel contains a vitamin E acetate having antioxidant and anti-free radical properties;
the release film adheres to the bottom of the drug layer and comprises a first-release film piece and a second-release film piece; the first-release film piece and the second-release film piece adhere to the drug layer, and adjacent edges of the first-release film piece and the second-release film piece are partially overlapped; and wherein
the antibiotic layer, the support layer, the drug layer, the release film, and the waterproof-breathable adhesive layer are rounded;
each layer has sides with a length and a width and the length and the width of each of the antibiotic layer, the support layer, and the drug layer are less than the length and the width of each of the release film and the waterproof-breathable adhesive layer; and
the waterproof-breathable adhesive layer, and the release film are bonded and adhered at an edge around the edged cataplasm.

### Claim 2 (depends on 1)

The edged cataplasm according to claim 1, wherein
a first part and a second part of the PET film adhere to both sides of the waterproof-breathable adhesive layer respectively, and adjacent edges of the first part and the second part are arranged as an aligned S-shaped edge.