# US 12,594,228 B2 · Composition for hair protection or hair strengthening

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- Number: US 12,594,228 B2
- Document ID: US12594228B2
- Status: Granted
- Kind: B2
- Application number: 19/077,514
- Filed: 2025-03-12
- Published: 2026-02-05
- Granted: 2026-04-07
- Earliest claimed: 2024-07-31
- Assignees: Amorepacific Corporation
- Applicants: Amorepacific Corporation
- Inventors: Chan Su Rha; Byeonggyu In; Soo Jin Lee; Chang Jo Jung; Byoung Young Woo; Kilsun Myoung; Eunsil Han
- Web page: https://patentgrep.com/patent/US12594228B2

## CPC

- A61K 8/64: Proteins; Peptides; Derivatives or degradation products thereof
- A61Q 5/002: {Preparations for repairing the hair, e.g. hair cure}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

A composition for hair protection or hair strengthening is disclosed. The composition may include i) a peptide including one or more sequence units of Xaa-Yaa-Zaa (wherein the Xaa, Yaa, and Zaa are each selected from C (cysteine), K (lysine), W (tryptophan), V (valine), L (leucine), or F (phenylalanine), and wherein the Xaa, Yaa, and Zaa are all different, and wherein, when Xaa and Yaa are C and K, respectively, Zaa is not L); ii) a peptide derivative in which a fatty acid or an organic acid is bound to the N-terminus of the peptide; or iii) at least three amino acids selected from C, K, W, V, L, or F.

## Claims

### Claim 1

A hair cosmetic composition for hair protection, damaged hair repair, or hair strengthening, comprising:
a peptide or a peptide derivative in an amount effective to protect hair, repair damaged hair, or strengthen hair,
wherein the peptide is KCV (Lys-Cys-Val), and
wherein the peptide derivative is KCV having a palmitoyl group bound to the N-terminus (palmitoyl-Lys-Cys-Val),
wherein the hair is head hair, eyebrows, and/or eyelashes; and
wherein the hair cosmetic composition is selected from the group consisting of hair shampoo, hair rinse, hair conditioner, hair cream, hair oil, hair lotion, hair tonic, hair mist, hair treatment, hair serum, hair mousse, hair wax, hair essence, hair spray, eyebrow serum, eyebrow essence, eyelash serum, and eyelash essence.

### Claim 2 (depends on 1)

The hair cosmetic composition according to claim 1, wherein the effective amount of the peptide or the peptide derivative is 5 to 20 mg per 1 g of hair.