# US 12,594,163 B2 · Tissue gripper and valve clamping device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 12,594,163 B2 - Document ID: US12594163B2 - Status: Granted - Kind: B2 - Application number: 18/112,513 - Filed: 2023-02-22 - Published: 2023-06-29 - Granted: 2026-04-07 - Earliest claimed: 2020-08-21 - Assignees: Hangzhou Valgen Medtech Co., Ltd. - Applicants: Hangzhou Valgen Medtech Co., Ltd. - Inventors: Tingchao Zhang; Weiwei Zhang; Xianzhang Zheng; Yiwei He - Web page: https://patentgrep.com/patent/US12594163B2 ## CPC - A61F 2/246: {Devices for obstructing a leak through a native valve in a closed condition} - A61F 2210/0014: using shape memory or superelastic materials, e.g. nitinol - A61F 2220/0016: with sharp anchoring protrusions, e.g. barbs, pins, spikes - A61F 2220/0025: Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements - A61F 2220/0091: connected by a hinged linkage mechanism, e.g. of the single-bar or multi-bar linkage type - A61F 2250/0006: for adjusting angular orientation - A61F 2250/0036: differing in thickness - A61F 2250/0037: differing in height or in length - A61F 2250/0069: Sealing means - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract A tissue gripper (60), includes a connecting frame (62) and two gripping arms (64). The connecting frame (62) includes two spaced connecting pieces (623), and the two gripping arms (64) are respectively arranged at sides of the two connecting pieces (623). Each gripping arm (64) includes a bending section (641) connected to the corresponding connecting piece (623) and a gripping section (643) connected to the bending section (641). The width of the bending section (641) is less than the width of the gripping section (643) and the width of the connecting piece (623), such that the weight of a valve clamping device (100) can be reduced, and the pulling force to pull the two gripping arms (64) up to a central axis can also be reduced. Also provided is the valve clamping device (100) provided with the tissue gripper (60). ## Claims ### Claim 1 A tissue gripper, comprising: a connection frame, the connection frame comprising two connection pieces spaced apart and opposite to each other; two gripping arms, the two gripping arms respectively arranged on sides of the connection pieces, each of the gripping arms extending away from the other one of the gripping arms, and each of the gripping arms comprising a bending section connected to the corresponding connection piece, and a gripping section connected to the bending section and extending away from the corresponding connection piece, a width of the bending section being less than a width of the gripping section, and less than a width of the corresponding connection piece; wherein each of the connection pieces is connected to the corresponding bending section through a bent fixing piece, the fixing piece on the corresponding connection piece bending toward the other one of the connection pieces, and each of the bending sections bending away from the other one of the bending sections; wherein each of the bending sections includes a first end connected to the corresponding fixing piece, and a second end connected to the corresponding gripping section, a width of the bending section at the first end is greater than a width of the bending section at the second end; wherein the width of the bending section gradually decreases from the first end to the second end. ### Claim 2 (depends on 1) The tissue gripper according to claim 1, wherein the width of the first end of the bending section is equal to the width of the fixing piece, the width of the second end of the bending section is equal to the width of the gripping section, and the bending section has a smooth transition from the first end to the second end. ### Claim 3 (depends on 1) The tissue gripper according to claim 1, wherein the gripping section of each of the gripping arms is provided with at least one row of barbs along a length direction thereof. ### Claim 4 (depends on 3) The tissue gripper according to claim 3, wherein an end of each of the at least one row of barbs is rounded. ### Claim 5 (depends on 3) The tissue gripper according to claim 3, wherein extension lengths of the barbs in the at least one row of barbs gradually increase along an extension direction of the gripping arm. ### Claim 6 (depends on 3) The tissue gripper according to claim 3, wherein included angles between the barbs in the at least one row of barbs and the corresponding gripping section gradually increases along an extending direction of the respective gripping arm. ### Claim 7 (depends on 1) The tissue gripper according to claim 1, wherein a bending portion is provided between the gripping section and the corresponding bending section of each of the gripping arms, and the bending portion is bent toward a side away from the connection frame. ### Claim 8 (depends on 1) The tissue gripper according to claim 1, wherein the tissue gripper is at least partially made of shape memory material, and the tissue gripper has a natural unfolded state and a folded state. ### Claim 9 (depends on 8) The tissue gripper according to claim 8, wherein the bending section is made of shape memory material, and an angle between the gripping sections of the two gripping arms is greater than 180 degrees in the natural state of the tissue gripper. ### Claim 10 (depends on 1) A valve clamping device, comprising: a fixing base; a pair of clamping arms, wherein the pair of clamping arms are configured to open and close relative to the fixing base; and a tissue gripper according to claim 1, the tissue gripper being arranged between the fixing base and the pair of clamping arms, each of the gripping arms of the tissue gripper is configured to cooperate with one of the pair of clamping arms to clamp a leaflet. ### Claim 11 (depends on 10) The valve clamping device according to claim 10, wherein the fixing base is accommodated in the connection frame, at least one of the connection pieces of the connection frame is provided with a slot, and the fixing base is provided with a protrusion engaged in the slot. ### Claim 12 (depends on 11) The valve clamping device according to claim 11, wherein a curvature radius of a proximal portion of the fixing base is greater than a curvature radius of the fixing piece.