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US 12,594,156 B2Granted
Prosthesis for the lung and the use thereof
AssigneeNational Institute of Biological Sciences, Beijing
InventorsNan Tang, Huijuan Wu, Jiao Li
Life of this patent
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Abstract
The invention relates to prosthesis for treating pulmonary fibrosis, in particular, idiopathic pulmonary fibrosis (IPF), and a method for treating pulmonary fibrosis, in particular, idiopathic pulmonary fibrosis (IPF).
Claims16
A method for treating pulmonary fibrosis, comprising following steps:
- reducing mechanical tension on the alveolar epithelium at an end of normal inspiratory, by placing a prosthesis under a pulmonary lobe of a lung in the pleural cavity of a subject so as to reduce the level of mechanical tension on the alveolar epithelium at the end of normal inspiratory, wherein the subject has pulmonary fibrosis in the lung;
- and attenuating progression of the pulmonary fibrosis of the subject,
- wherein the prosthesis is in a shape of plate, ellipse, irregular U, arc, conical, scapula, or irregular, so as to occupy the space under the lung lobe,
- wherein the prosthesis is solid,
- wherein the prosthesis is made of soft spongy latex, foam latex, 380 micron hollow fiber, gelatin foam, plastic sponge, rubber, silicone rubber, silicone gel, carbon nanotube, graphene, ultra-light porous carbon, hollow porous carbon, carbon fiber, or carbon titanium alloy,
- wherein the prosthesis occupies at least ¼ of a space surrounded by a basal area of the pulmonary lobe, diaphragm and a wall of pleural cavity at the end of normal inspiratory,
- wherein the prosthesis comprises a body having an upper side, a lower side, a lateral side extending between the upper side and the lower side, and a medial border approaching the heart, wherein the lateral side is opposite to the medial border, and
- wherein the lateral side is at a height of 0.5 cm-8 cm, and thickness of a wall of the prosthesis is between 0.1-4 cm.
5 more elements
Dependencies are inferred from the claim text.