Method for predicting formation of thrombus or risk of thrombus formation in medical device performing blood circulation by pump
AssigneeTerumo Kabushiki Kaisha
InventorsIchiro Hirahara, Shinpei Furukawa, Koko Kumano, Hideki Sato
Life of this patent
Estimating the term…
Abstract
Provided is a means capable of predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, by a simple and minimally invasive method. A method for predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, wherein it is predicted that thrombus is formed or there is a risk thereof in the medical device when a concentration or expression amount of ADAM28 in a body fluid sample collected from a subject wearing the medical device is elevated compared with a reference value.
Claims4
A method for reducing thrombus formation in a patient requiring insertion of a medical device into the patient to perform blood circulation, the method comprising:
- measuring a concentration or amount of ADAM28 in a first fluid body sample collected from the patient before the medical device is inserted into the patient;
- inserting the medical device into the patient;
- collecting a second fluid body sample from the patient after the inserting of the medical device into the patient;
- measuring a concentration or amount of ADAM28 in the collected second fluid body sample from the patient;
- and
- when the concentration or amount of ADAM28 in the collected second fluid body sample from the patient is higher than the concentration or amount of ADAM28 in the first fluid body sample collected from the patient before the inserting of the medical device, administering an anticoagulation treatment to the patient to reduce thrombus formation during use of the medical device.
Dependencies are inferred from the claim text.