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AssigneesVentana Medical Systems, Inc., Roche Diagnostics Operations, Inc., Roche Diagnostics Hematology, Inc.
InventorsSrabani Bhaumik, Simon J. Davidson, Jerome W. Kosmeder, II, Katherine K. Mui, Esteban Roberts, Noemi Sebastiao, David J. Zahniser
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This disclosure relates generally to the use of automated platforms in the preparation of biomarker-stained cellular samples for microscopic analysis and use of such stained cells in the diagnosis of certain conditions. Disclosed herein is a method of affinity staining a Romanowsky-type stained sample on automated advanced staining systems, wherein the automated advanced stainer destains the sample prior to contact with a biomarker-specific reagent. Also disclosed herein are methods of processing body fluid samples for morphological and biomarker analysis by depositing cells of the sample in a thin layer onto one or more solid supports, staining at least one such solid support with a Romanowsky-type stain and staining at least one such solid support for one or more biomarkers useful for categorizing one or more cells of the sample.
An automated method of performing a cytological evaluation, the method comprising:
An automated method of performing a cytological evaluation, the method comprising:
An automated method of performing a cytological evaluation, the method comprising:
Dependencies are inferred from the claim text.