Back to results
US 12,590,164 B2Granted
Productivity-enhanced antibody and method for producing same
AssigneeYonsei University BioHealth Technology Holdings, Inc.
InventorsJoo Young Kim, Jinu Lee, Hye Yeon Kim
Life of this patent
Estimating the term…
Abstract
Provided herein is a method for producing an antibody with improved productivity while maintaining its titer by causing at least one hydroxyamino acid contained in the light chain of the antibody to undergo O-linked glycosylation. Also provided is an antibody so produced.
Claims4
An antibody comprising at least one glycosylated hydroxyamino acid residue in the light chain thereof comprising at least one glycosylated hydroxyamino acid residue at the 7th, 12th, 14th, 26th or 62nd position from the 5′ end of the light chain.
Dependencies are inferred from the claim text.