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US 12,590,132 B2Granted
FGF21 variant polypeptide molecules and application thereof
AssigneeSunshine Lake Pharma Co., Ltd.
InventorsChao Chen, Shushan Lin, Yu Li, Xiaoping Li, Xiaofeng Chen, Wenjia Li, Liang Liu, Zheng Fu
Life of this patent
Estimating the term…
Abstract
An FGF21 polypeptide has one or more of the following properties: stable structure, long half-life, low immunogenicity, high biological activity, and enhanced glucose-lowering and lipid-lowering activities. A fusion protein or immunoconjugate includes the FGF21 polypeptide.
Claims14
An FGF21 polypeptide comprising the amino acid sequence of SEQ ID NO:
- 2, 3, 5, 7, or 8.
Dependencies are inferred from the claim text.