Back to results
US 12,590,097 B2Granted
Substituted entecavir monophosphate alaninamide phenolic esters for resisting hepatitis b virus
AssigneeBeijing Junke Huayuan Med Tech Co., Ltd.
InventorsBohua Zhong, Hongwu Li, Xiaozai Wang
Life of this patent
Estimating the term…
Abstract
An entecavir monophosphate alaninamide phenolic ester derivative is represented by formula II. It has non-toxic pharmaceutically acceptable salts. In formula II, X is H, halogen, R or —OR, and R is a C1-3 alkyl or a substituted C1-3 alkyl. The entecavir monophosphate alaninamide phenolic ester derivative or the non-toxic pharmaceutically acceptable salt thereof can be used in the preparation of a drug for resisting the hepatitis B virus.
Claims11
A compound of formula II:
- or a non-toxic pharmaceutically acceptable salt thereof,
- wherein:
- X is H, halogen, R, or OR;
- and
- R is a C1-3 alkyl, wherein the C1-3 alkyl is optionally substituted with one or more substituents independently selected from the group consisting of halogen and OH.
2 more elements
Dependencies are inferred from the claim text.