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US 12,590,083 B2Granted
Inhibitors of spinster homolog 2 (SPNS2) for use in therapy
AssigneesUniversity of Virginia Patent Foundation, Virginia Tech Intellectual Properties, Inc.
InventorsKevin R. Lynch, Yugesh Kharel, Webster L. Santos, Ashley Peralta, Russell G. Fritzemeier, Daniel Foster
Life of this patent
Estimating the term…
Abstract
The present disclosure provides SPNS2 inhibitor compounds according to Formula I and their pharmaceutically acceptable salts, and/or tautomers as described in the disclosure, and the disclosure provides their pharmaceutical compositions and methods of use in therapy.
Claims2
A compound or pharmaceutically acceptable salt thereof, wherein the compound is selected from the following table:
- Com-
- pound
- Structure
- 5a
- 5e
- 5f
- 5g
- 5h
- 5j
- 51
- 5p
- 5q
- 5aa
- 13b
- 13c
- 13d
- 13e
- 13f
- 13g
- 13h
- 13i
- 13j
- 21c
- 21d
- 21e
- 21f
- 21g
- 21j
- 28d
- 28e
- 28f
- 28g
- 38a
- 38b
- 38c
- 38d
- 38g
- 38h
- 38i
- 38j
- 38k
- 38l
- 38n
- 38o
- 38p
42 more elements
Dependencies are inferred from the claim text.