Compounds

A compound of Formula (I) or a salt thereof:

• wherein R1 and R5 are each independently selected from the group consisting of halogen and C1-4alkyl,
• wherein R3 is selected from the group consisting of hydrogen, halogen, C1-6alkyl, —O—C1-6alkyl, C1-6haloalkyl, —O—C1-6haloalkyl, C2-6alkenyl, C2-6alkynyl, C3-10carbocyclyl, 3-10 membered heterocyclyl, —CN, —OR11, —SR11, —NR11R12, —COR11, —CO2R11, —CONR11R12, —NR11COR12, —SO2R11, —SO2NR11R12, and —NR11SO2R12,
• wherein said alkyl, alkenyl, alkynyl, carbocyclyl or heterocyclyl may be unsubstituted or substituted with one or more substituents each independently selected from the group consisting of halogen, C1-4alkyl, O—C1-4alkyl, C1-4haloalkyl, —O—C1-4haloalkyl, —CN, —OR11, —SR11, —NR11R12, —COR11, —CO2R11, —CONR11R12, —NR11COR12, —SO2R11, —SO2NR11R12, and —NR11SO2R12;
• R2 and R4 are each independently selected from the group consisting of hydrogen, halogen, C1-4alkyl, —O—C1-4alkyl, C1-4haloalkyl and —O—C1-4haloalkyl;
• n is an integer of from 0 to 2;
• X is S, O, or NH;
• R6 is selected from the group consisting of hydrogen, halogen, C1-4alkyl, —O—C1-4alkyl,
• C1-4haloalkyl and —O—C1-4haloalkyl;
• R7 is selected from the group consisting of hydrogen, halogen, —CN, —C1-6 alkyl, C3-10carbocyclyl, C3-10heterocyclyl, —O—C1-6alkyl, —O—C3-10carbocyclyl, —O-(3-10 membered heterocyclyl), —NH(C1-6alkyl), —N(C1-6alkyl)2, —NH—C3-10carbocyclyl, —N(C1-4alkyl)-C6-10carbocyclyl, —NH-(3-10 membered heterocyclyl), —N(C1-4alkyl)-(3-10 membered heterocyclyl), —C(O)—C1-4alkyl, —C(O)—C3-10carbocyclyl, —C(O)-(3-10 membered heterocyclyl), and —C(O)N(C1-4alkyl)2,
• wherein said alkyl, carbocyclyl or heterocyclyl may be unsubstituted or substituted with up to two substituents each independently selected from the group consisting of C1-4alkyl, oxo, halogen and C1-4haloalkyl;
• R8 is selected from the group consisting of hydrogen, —C1-8alkyl, —O—C1-8 alkyl, —C1-4alkylene-R13, —O—C1-4alkylene-R13 and —O—R13;
• R9 is selected from the group consisting of hydrogen and halogen;
• R10 is selected from the group consisting of hydrogen, C1-6alkyl, C1-6haloalkyl, C6-10aryl, —R14, —C1-6alkylene-R14, —C6-10arylene-R14, —NH—C1-6alkyl-R14, and —NH—C(O)—C1-6alkyl-R14;
• wherein said aryl or arylene may optionally be substituted with one or two substituents each independently selected from the group consisting of C1-4alkyl, halogen and C1-4haloalkyl;
• if present, each R11 and R12 is independently selected from the group consisting of hydrogen, C1-6alkyl, C3-10carbocyclyl, and 3-10 membered heterocyclyl;
• if present, R13 is selected from the group consisting of hydrogen, —C1-6 alkyl, halogen, —CN, C3-10carbocyclyl, 3-10 membered heterocyclyl, —O—C1-6alkyl, —O—C3-10carbocyclyl, —O-(3-10 membered heterocyclyl), —NH(C1-6alkyl), —N(C1-6alkyl)2, —NH—C3-10carbocyclyl, —N(C1-4alkyl)-C6-10carbocyclyl, —NH-(3-10 membered heterocyclyl), —N(C1-4alkyl)-(3-10 membered heterocyclyl), —C(O)—C1-4alkyl, —C(O)—C3-10carbocyclyl, —C(O)-(3-10 membered heterocyclyl), and —C(O)N(C1-4alkyl)2,
• wherein said alkyl, carbocyclyl or heterocyclyl may be unsubstituted or substituted with up to two substituents each independently selected from the group consisting of C1-4alkyl, oxo, halogen and C1-4haloalkyl;
• and
• if present, R14 is selected from the group consisting of —NH2, C3-10heterocyclyl, —O—C3-10heterocyclyl, —NH—C3-10heterocyclyl and —N(Me)-C3-10heterocyclyl;
• wherein said heterocyclyl may be unsubstituted or substituted with up to three substituents each independently selected from C1-4alkyl, oxo, halogen and C1-4haloalkyl.