Phenol derivative
AssigneeSumitomo Pharma Co., Ltd.
InventorsKozo Yoshida, Hiroyuki Kitano, Yuki Mizukami
Life of this patent
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Abstract
A compound represented by formula (2) or pharmaceutically acceptable salt thereof: wherein R1 represents a hydrogen atom or the like; R2 represents a methoxy group or the like; R3 represents a hydrogen atom or the like; R4 represents an optionally substituted C1-6 alkyl group or the like; m represents 0, 1, or 2; n represents 0, 1, 2, or 3; L1 represents —NH—C(═O)—, —C(═O)—NH—, or the like; L2 represents a single bond or the like; X represents optionally substituted phenyl or the like; Y represents optionally substituted phenyl or the like; and X and Y are bonded at a carbon atom on each ring.
Claims27
A compound or pharmaceutically acceptable salt thereof, having a structure:
- 3-{6-[2-(4-hydroxy-3-methoxyphenyl)acetamido]pyridin-2-yl}phenyl 2-methylpropanoate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido)phenyl}cyclohexyl cyclohexanecarboxylate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido]phenyl}cyclohexyl (3-methylphenyl)acetate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido]phenyl}cyclohexyl (2-chlorophenyl)acetate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido]phenyl}cyclohexyl acetate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido]phenyl}cyclohexyl (2-fluorophenyl)acetate;
- cis-4-{3-[2-(4-hydroxy-3-methoxyphenyl)acetamido]phenyl}cyclohexyl (2-methylpropanoate;
- 2′-fluoro-5′-[2-(4-hydroxy-3′-methoxyphenyl)acetamido][1,1′-biphenyl-3-yl 2-methylpropanoate;
- 3′-[2-(4-hydroxy-3-methoxyphenyl)acetamido][1,1′-biphenyl]-3-yl 2-methylpropanoate;
- 3′-{4-[2-(4-hydroxy-3-methoxyphenyl)acetamido]pyridin-2-yl}phenyl 2-methylpropanoate;
- 3-(4-{[(4-hydroxy-3-methoxyphenyl)methyl]carbamoyl}pyridin-2-yl)phenyl 2-methylpropanoate;
- or
- 3-{4-2-4-hydroxy-3-methoxyphenyl)acetamido]pyridin-2-yl}phenyl 2-methylpropanoate hydrochloride.
Dependencies are inferred from the claim text.