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US 12,589,249 B2Granted
Medical device and method for cardiac pacing of the his-purkinje conduction system
AssigneeMedtronic, Inc.
InventorsJian Cao, Xiaohong Zhou
Life of this patent
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Abstract
A medical device is configured to deliver His-Purkinje pacing pulses according to multiple settings of a pacing control parameter and determine an electromechanical time delay from a ventricular electrical event to a fiducial point of the pressure signal for each of the pacing control parameter settings. The medical device may be configured to select an operating pacing control parameter from the pacing control parameter settings based on a determined electromechanical time delay being less than a threshold interval. The medical device may deliver pacing pulses to the His-Purkinje conduction system according to the selected operating pacing control parameter.
Claims19
A medical device, comprising:
- a therapy delivery circuit configured to deliver at least one His-Purkinje pacing pulse according to each of a plurality of settings of a pacing control parameter;
- a pressure sensor configured to sense a first pressure signal;
- and
- a processing circuit configured to:
- for each of the plurality of settings of the pacing control parameter:
- identify a ventricular electrical event;
- identify a fiducial point of the first pressure signal following the ventricular electrical event;
- determine an electromechanical time delay from the ventricular electrical event to the fiducial point of the first pressure signal;
- identify from among the plurality of settings of the pacing control parameter each pacing control parameter setting that is associated with a determined electromechanical time delay that is less than a threshold interval;
- and
- for each of the identified pacing control parameter settings associated with a determined electromechanical time delay that is less than the threshold interval, determine a maximum slope amplitude of the pressure signal;
- select an operating pacing control parameter from the identified pacing control parameter settings as one of the identified pacing control parameter settings that is associated with a greatest maximum slope amplitude of the determined maximum slope amplitudes;
- wherein the therapy delivery circuit is configured to deliver His-Purkinje pacing pulses according to the selected operating pacing control parameter.
10 more elements
A method, comprising:
- delivering at least one His-Purkinje pacing pulse according to each of a plurality of settings of a pacing control parameter;
- sensing a first pressure signal;
- for each of the plurality of settings of the pacing control parameter:
- identifying a ventricular electrical event;
- identifying a fiducial point of the first pressure signal following the ventricular electrical event;
- and
- determining an electromechanical time delay from the ventricular electrical event to the fiducial point of the first pressure signal;
- identifying from among the plurality of settings of the pacing control parameter each of the pacing control parameter settings that is associated with a determined electromechanical time delay that is less than a threshold interval;
- for each of the identified pacing control parameter settings associated with a determined electromechanical time delay that is less than the threshold interval, determining a maximum slope amplitude of the pressure signal;
- selecting an operating pacing control parameter from the identified pacing control parameter settings that is associated with a greatest maximum slope amplitude of the determined maximum slope amplitudes;
- and
- delivering His-Purkinje pacing pulses according to the selected operating pacing control parameter.
9 more elements
A non-transitory, computer-readable storage medium comprising a set of instructions which, when executed by a processing circuit of a medical device cause the medical device to:
- deliver at least one His-Purkinje pacing pulse according to each of a plurality of settings of a pacing control parameter;
- sense a pressure signal;
- for each of the plurality of settings of the pacing control parameter:
- identify a ventricular electrical event;
- identify a fiducial point of the pressure signal following the ventricular electrical event;
- and
- determine an electromechanical time delay from the ventricular electrical event to the fiducial point of the pressure signal;
- identify from among the plurality of settings of the pacing control parameter each of the pacing control parameter settings that is associated with a determined electromechanical time delay that is less than a threshold interval;
- for each of the identified pacing control parameter settings associated with a determined electromechanical time delay that is less than the threshold interval, determine a maximum slope amplitude of the pressure signal;
- select an operating pacing control parameter from the identified pacing control parameter settings that is associated with a greatest maximum slope amplitude of the determined maximum slope amplitudes;
- and
- deliver His-Purkinje pacing pulses according to the selected operating pacing control parameter.
9 more elements
Dependencies are inferred from the claim text.