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US 12,589,162 B2Granted
Trans-cyclooctene prodrug of monomethyl auristatin E
AssigneeTambo, Inc.
InventorsJose Manuel Mejia Oneto, Nathan A. Yee, Jesse M. McFarland
Life of this patent
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Abstract
6-(Carbonyloxy)-1-methylcyclooct-4-ene-1-carbonyl)-aspartic acid conjugate of monomethyl auristatin E may be used for bioorthogonal delivery to a targeted location in a subject in the treatment of cancer and tumor growths.
Claims4
A compound:
- or a pharmaceutically acceptable salt thereof.
A compound:
Dependencies are inferred from the claim text.