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US 12,589,151 B2Granted
T cell modification
AssigneeUswm Ct, LLC
InventorsLuca Melchiori, Joanna Brewer
Life of this patent
Estimating the term…
Abstract
The present invention provides a modified T cell or population of modified T cells comprising a heterologous recombinant T cell receptor (TCR) and heterologous recombinant co-receptor, additionally provided are methods of producing the modified T cell or population of modified T cells and their use in the treatment of cancer.
Claims8
An isolated modified T cell or a population of isolated modified T cells comprising a heterologous homodimeric CD8αco-receptor and a heterologous T cell receptor (TCR) that binds MAGE-A4.
Dependencies are inferred from the claim text.