Back to results
US 12,589,143 B2Granted
Human anti-PD-L1 peptide vaccines and methods of their use
AssigneeOhio State Innovation Foundation
InventorPravin T.P. Kaumaya
Life of this patent
Estimating the term…
Abstract
Disclosed are compositions related to synthetic PD-L1 peptides, chimeric PD-L1 peptides, anti-PD-L1 antibodies and methods of treating cancers, autoimmune diseases, and Alzheimer's disease using said peptides or antibodies.
Claims20
A programmed cell death ligand-1 (PD-L1) chimeric peptide for stimulating an immune response to a PD-L1 protein comprising one or more PD-L1 B cell epitopes, a T helper (Th) epitope, and a linker joining the PD-L1 B cell epitope to the Th epitope, wherein the one or more PD-L1 B cell epitopes consist of a sequence selected from the group consisting of SEQ ID NO:
- 2, SEQ ID NO:
- 3, SEQ ID NO:
- 4, and SEQ ID NO:
- 5.
1 more element
Dependencies are inferred from the claim text.