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US 12,589,135 B2Granted
Topical administration of GLP-1 receptor agonists
AssigneeCMPD Licensing, LLC
InventorsDaniel Banov, Gus Bassani, Jay Richard Ray, II
Life of this patent
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Abstract
A method of treating type-2 diabetes, chronic weight maintenance, or overindulgence conditions includes administering a pharmaceutically effective amount of a topical composition comprising a GLP-1 receptor agonist suspended in an anhydrous suspension base vehicle to an oral cavity of a subject for oral absorption therein. The topical composition is formulated to form a self-emulsifying liposome in an aqueous environment of the oral cavity.
Claims15
A method of treating type-2 diabetes, chronic weight maintenance, or overindulgence conditions, the method comprising:
- administering a topical composition to an oral cavity of a subject for oral absorption therein, the topical composition comprising a pharmaceutically effective amount of semaglutide suspended in an anhydrous liquid comprising phosphatidylcholine, lysophosphatidylcholine, caprylic/capric triglyceride, polycarbophil, glyceryl distearate, and glyceryl monostearate, wherein the topical composition is self-emulsifying and forms mixed micelles and liposomes associated with the semaglutide in an aqueous environment of the oral cavity.
Dependencies are inferred from the claim text.