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US 12,589,130 B2Granted
Aloe extracts for microbial neutralisation
Assignee2QR Research B.V.
InventorsFloris Koumans, Paul Kwakman
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Abstract
The present invention relates to a composition comprising polysaccharides derivable from Aloe vera with aggregating activity towards microorganisms and to its use in preventing or treating infections. The composition having an average molecular weight in the range of 30-100 kDa and comprising 80-100% w/w mannose and 0-5% w/w glucose.
Claims14
A composition comprising polysaccharides derivable from Aloe vera, the composition comprising:
- 80-100% w/w mannose;
- and
- 0-5% w/w glucose by weight of total polysaccharides,
- wherein the composition is capable of an aggregating activity towards microorganisms if contacted therewith,
- wherein the composition is obtained as flow through fraction not bound to an anion exchange column at pH 7, and
- wherein the polysaccharides in the composition have an apparent molecular weight in the range of 30-100 kDa, as determined by ultrafiltration.
3 more elements
A method for treatment or prevention of an infection by a microorganism in a human or animal body, comprising the steps of:
- administering to a human or animal subject, a composition comprising:
- 80-100% w/w mannose;
- and
- 0-5% w/w glucose by weight of total polysaccharides,
- wherein the composition is capable of an aggregating activity towards microorganisms if contacted therewith,
- wherein the composition is obtained as flow through fraction not bound to an anion exchange column at pH 7, and
- wherein the polysaccharides in the composition have an apparent molecular weight in the range of 30-100 kDa, as determined by ultrafiltration.
4 more elements
Dependencies are inferred from the claim text.