Injectable bifunctional hydrogel with antibacterial activity as well as the preparative method and the use thereof
AssigneeSichuan University
InventorsHang Zhao, Jiang Liu, Yanan Zhang, Xianglong Han, Qianming Chen
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Abstract
An injectable bifunctional hydrogel has antibacterial activity. The bifunctional hydrogel is a hydrogel prepared by dissolving nucleoside analogues in a solvent. The nucleoside analog has a structure of formula I. It can be a candidate drug for the local injection treatment of periodontal disease, and it also has potential application prospects in the minimally invasive treatment of craniofacial bone tissue defects.
Claims8
A hydrogel, comprising a 3-D network consisting of nucleoside analog of Formula I and a solvent, wherein a concentration of the nucleoside analog in the hydrogel is 2.5 w/v % to 5 w/v %,
- wherein the solvent is water or phosphate-buffered saline.
Dependencies are inferred from the claim text.