Composition containing nicotinamide mononucleotide and mogroside, and application thereof
AssigneesBeijing Hebabiz Biotechnology Co., Inc., Beijing Hebabiz Management Co., Ltd.
InventorsJames Zhou, Bai-Bo Xie, Xinyu Zang
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Abstract
The present invention belongs to the medical and technical field and provides a medicine or health food composition of nicotinamide mononucleotide and mogroside. In addition, the present invention also provides the preparation method, formulation and application of the composition.
Claims17
A pharmaceutical composition comprising nicotinamide mononucleotide and mogroside, wherein the molar ratio of nicotinamide mononucleotide:mogroside is 1-2:1-5;
- mogroside is mogroside V or a Corsvenor Momordica Fruit extract containing mogroside V;
- and the method for extracting mogroside includes the following steps:
- (1) Corsvenor Momordica Fruit is extracted by heating with water and filtered;
- (2) the filtrate obtained in step (1) is purified with a D101 macroporous resin chromatography column, and the eluent eluted with 35-45% (V/V) ethanol is collected and concentrated;
- and
- (3) the concentrated solution obtained in step (2) is purified with an ADS-7 macroporous resin chromatography column, and the eluate eluted with 25-35% (V/V) ethanol is collected and concentrated to dryness.
A health food composition comprising nicotinamide mononucleotide and mogroside, wherein the molar ratio of nicotinamide mononucleotide:mogroside is 1-2:1-5;
- mogroside is mogroside V or a Corsvenor Momordica Fruit extract containing mogroside V;
- and the method for extracting mogroside includes the following steps:
- (1) Corsvenor Momordica Fruit is extracted by heating with water and filtered;
- (2) the filtrate obtained in step (1) is purified with a D101 macroporous resin chromatography column, and the eluent eluted with 35-45% (V/V) ethanol is collected and concentrated;
- and
- (3) the concentrated solution obtained in step (2) is purified with an ADS-7 macroporous resin chromatography column, and the eluate eluted with 25-35% (V/V) ethanol is collected and concentrated to dryness.
Dependencies are inferred from the claim text.