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US 12,589,095 B2Granted
Unit dosage form for transmucosal drug delivery of an active pharmaceutical ingredient
AssigneePrimo Pharmatech LLC
InventorZheng Wang
Life of this patent
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Abstract
A novel unit dosage form for oral transmucosal delivery of an active pharmaceutical ingredient (API). The dosage form contains a permeation enhancer that promotes fast absorption, rapid onset of action, and overall high bio availability for the API.
Claims6
A unit dosage form formulated for oral transmucosal delivery of an active pharmaceutical ingredient (API), comprising:
- a therapeutically effective amount of the API and a permeation enhancer, wherein the permeation enhancer is in an effective amount to enhance the penetration of the API of the unit dosage form through oral mucosa, and wherein the permeation enhancer comprises polyoxytheylene sorbitan monooleate and oleic acid, wherein the permeation enhancer has a HLB value ranging from about 8 to about 11, wherein the API is octreotide or oxytocin.
Dependencies are inferred from the claim text.