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US 12,589,084 B2Granted
Choline bolus compositions for ruminants
AssigneeAlberta Veterinary Laboratories Ltd.
InventorMerle Olson
Life of this patent
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Abstract
Disclosed are bolus compositions for use in the treatment or prevention of hypocalcemia and choline deficiency in ruminants. The bolus compositions may comprise rumen-protected choline, one or more calcium salts, and water.
Claims16
A solid bolus composition for the simultaneous prevention or treatment of hypocalcemia and a choline deficiency in a ruminant, comprising:
- an inner mass comprising:
- a rumen-protected choline at about 5 wt % to about 20 wt % of the solid bolus composition;
- one or more calcium salts at about 65 wt % to about 85 wt % of the solid bolus composition;
- water at about 15 wt % to about 25 wt % of the solid bolus composition;
- and
- a binder at about 0.1 wt % to about 1 wt % of the solid bolus composition, and
- an outer mass being a coating comprising acetyl esters of triglycerides capable of passage through the esophagus for dissolution in the rumen of the ruminant to release the rumen-protected choline and the one or more calcium salts into the rumen,
- wherein the solid bolus composition has a total weight of between about 200 g and about 250 g and is for administration to the ruminant using a balling gun.
5 more elements
Dependencies are inferred from the claim text.