Ocular delivery systems and methods
AssigneeSight Sciences, Inc.
InventorsDavid Y. Badawi, Daniel O'Keeffe, Paul Badawi
Life of this patent
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Abstract
Described here are systems and methods for accessing Schlemm's canal and for delivering an ocular device or fluid composition therein. The ocular devices may maintain the patency of Schlemm's canal without substantially interfering with transmural fluid flow across the canal. The fluid composition may be a viscoelastic fluid that is delivered into the canal to facilitate drainage of aqueous humor by disrupting the canal and surrounding trabeculocanalicular tissues. Tools for disrupting these tissues and minimally invasive methods for treating medical conditions associated with elevated intraocular pressure, including glaucoma, are also described.
Claims30
A method for reducing intraocular pressure of an eye comprising:
- advancing a device at least partially through an anterior chamber of the eye and into Schlemm's canal, wherein the device comprises a conduit for delivering viscoelastic fluid to Schlemm's canal;
- advancing the conduit along an arc of Schlemm's canal;
- delivering about 8 μl to about 50 μl of viscoelastic fluid to Schlemm's canal to dilate associated collector channels;
- and
- delivering an ocular device to Schlemm's canal, wherein the ocular device comprises a suture.
A method for reducing intraocular pressure comprising:
- advancing a device at least partially through an anterior chamber of an eye and into Schlemm's canal, wherein the device comprises a conduit for delivering viscoelastic fluid to Schlemm's canal;
- advancing the conduit along an arc of Schlemm's canal;
- delivering about 20 μl of viscoelastic fluid to Schlemm's canal;
- and
- after delivering the about 20 μl of viscoelastic fluid, delivering an ocular device comprising a suture to Schlemm's canal.
A method for reducing intraocular pressure comprising:
- advancing a device at least partially through an anterior chamber of an eye and into Schlemm's canal, wherein the device comprises a conduit for delivering viscoelastic fluid to Schlemm's canal;
- advancing the conduit along an arc of Schlemm's canal;
- delivering about 8 μl of viscoelastic fluid to Schlemm's canal while retracting the conduit;
- and
- delivering an ocular device to Schlemm's canal to maintain patency of the canal, wherein the ocular device comprises a suture.
Dependencies are inferred from the claim text.