Devices, systems and methods for repairing lumenal systems

A system for delivering a prosthesis to a target location, comprising:

• a) a tether delivery catheter for delivering an anchored tether to an anatomical location, including:
• i) an elongate torqueable drive shaft having a proximal end with a first handle attached thereto and a distal end having a coupling for receiving an anchor;
• ii) an anchor received in a torqueable relationship with the coupling of the distal end of the elongate torqueable drive shaft, the anchor having an anchoring portion to be advanced into an anatomical location, and at least one elongate tether extending proximally from the anchor toward the first handle;
• and
• iii) an outer tubular member having a proximal end, a distal end and an elongate body surrounding the elongate torqueable drive shaft, the outer tubular member including a handle proximate its proximal end, the second handle being rotatable with respect to the first handle about a central axis of the catheter to permit the anchor and elongate torqueable drive shaft to be rotated with respect to the outer tubular member;
• and
• b) a prosthesis delivery catheter, including:
• i) an elongate inner body having a proximal portion and a distal tip, the distal tip including a first proximally extending tubular member having a freely floating proximal end, the first proximally extending tubular member and elongate inner body cooperating to define a first substantially annular chamber;
• ii) an elongate tubular outer body having a proximal portion and a distal end, the elongate tubular outer body being disposed about a proximal region of the elongate inner body, the elongate tubular outer body being axially displaceable with respect to the elongate inner body, the distal end of the elongate tubular outer body being configured to substantially abut the proximal end of the first proximally extending tubular member, a distal region of the elongate tubular outer body and the proximal region of the elongate inner body cooperating to define a second substantially annular chamber, the first and second chambers cooperating to define a prosthesis chamber for receiving a compressed prosthesis;
• and
• iii) a compressed prosthesis disposed about the elongate inner body in the prosthesis chamber, the compressed prosthesis having at least one rail eyelet for receiving a flexible rail, the at least one rail eyelet extending radially outwardly through a juncture defined between the distal end of the elongate tubular outer body and the proximal end of the first proximally extending tubular member, the compressed prosthesis being configured to expand radially outwardly when the elongate inner body is advanced distally with respect to the elongate tubular outer body, and further wherein the elongate inner body and tubular outer body can be withdrawn proximally through a lumen defined by the prosthesis after deployment of the prosthesis without needing to disturb the prosthesis or anything in physical contact with the prosthesis.