Method for monitoring lung integrity
AssigneeBoard of Regents, The University of Texas System
InventorsDaniel T. DeArmond, Lucas M. Holt, Andrew P. Wang
Life of this patent
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Abstract
The present invention relates to systems and methods for monitoring impedance from a sensor in the chest of a subject to determine the status of lung inflation or presence of pneumothorax in the subject, the presence of pulmonary edema, the status of regional lung ventilation, and the status of cardiac contractility.
Claims12
A method for detecting lung collapse in a subject having a chest tube or other device implanted into the pleural space wherein a monitoring system comprising an impedance measuring circuit, a suction control circuit, and microcontroller performs steps comprising:
- a. determining initial impedance measured by a sensor in the chest cavity to determine presence or absence of impedance rail signal in the impedance measurement;
- b. continuing monitoring if no impedance rail is detected or applying suction for a predetermined period of time if an impedance rail is detected for a pre-determined period of time without suction;
- c. reducing suction after a pre-determined period of time;
- d. determining impedance after suction is reduced and determine presence or absence of impedance rail signal in impedance measurement;
- and
- e. continue monitoring if no impedance rail is detected or applying suction if impedance rail signal is detected for a pre-determined period of time and repeat steps (c) and (d).
A method for detecting regional lung ventilation in a subject (i) ventilated by a mechanical ventilator, (ii) having a chest tube or other device implanted into the pleural space with the ability to measure electrical impedance from the surface of the lung and (iii) having a pressure sensor measuring intra-airway pressure comprising monitoring the subject with a monitoring system comprising a sensor for measuring airway pressure, an impedance measuring circuit, a mechanical ventilator control circuit, and microcontroller, monitoring steps comprising:
- a. determining initial intra-airway pressure, initial peak lung impedance, initial average lung impedance, and initial amplitude of the respiratory impedance waveform measured by the sensors in the chest cavity to determine the degree of regional lung ventilation and calculating a value for the aeration index (AI) as given by:
- (RP−RT)/PIP or (ZP−ZT)/PIP;
- b. reducing or increasing ventilator tidal volume according to a pre-determined algorithm after a pre-determined period of time;
- c. determining intra-airway pressure, peak lung impedance, average lung impedance, and amplitude of the respiratory impedance waveform and from these calculating the value for aeration index (AI) after tidal volume is reduced or increased and determine whether regional lung ventilation 1s improved or diminished with respect to intra-airway pressure;
- and
- d. continue monitoring if regional lung ventilation is improved with respect to intra-airway pressure based on the value for AI or reducing or increasing tidal volume according to a pre-determined algorithm for a pre-determined period of time and repeat steps (b) and (c).
A method for detecting pulmonary edema in a subject having a chest tube or other device implanted into the pleural space using a monitoring system comprising an impedance measuring circuit, a control circuit controlling diuretic medication and/or inotrope administration and/or intravenous fluid administration, and microcontroller to perform the steps comprising:
- a. determining initial lung impedance as measured by a sensor in the chest cavity to determine the degree of pulmonary edema;
- b. administering diuretic medication and/or inotropes and/or intravenous fluids by a predetermined algorithm after a pre-determined period of time;
- c. determining lung impedance after diuretic medication and/or inotrope and/or intravenous fluid delivery and determine whether pulmonary edema is increased or decreased;
- and
- d. continue monitoring if pulmonary edema is increased or decreased or administer diuretic medications and/or inotropes and/or intravenous fluids according to a predetermined algorithm for a pre-determined period of time and repeat steps (b) and (c).
A method for detecting cardiac contractility in a subject having a chest tube or other device implanted into the pleural or pericardial space using a monitoring system comprising an impedance measuring circuit, a control circuit controlling diuretic medication and/or inotrope and/or vasopressor and/or intravenous fluid administration, and microcontroller by performing the steps comprising:
- a. determining initial cardiac impedance as measured by a sensor in the chest cavity to determine the degree of cardiac contractility;
- b. administering diuretic medication and/or inotropes and/or vasopressors and/or intravenous fluids by a pre-determined algorithm after a pre-determined period of time;
- c. determining impedance after diuretic medication and/or inotrope and/or vasopressor and/or intravenous fluid delivery and determine whether cardiac contractility is increased or decreased;
- and
- d. continue monitoring if cardiac contractility is increased or decreased or administer diuretic medications and/or inotropes and/or vasopressors and/or intravenous fluids according to a pre-determined algorithm for a pre-determined period of time and repeat steps (b) and (c).
Dependencies are inferred from the claim text.