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US 12,586,662 B2Granted
Biological material analysis method, biological material analysis device, and biological material analysis program
AssigneeFUJIFILM Corporation
InventorKiyohiro Maeda
Life of this patent
Estimating the term…
Abstract
Time-series data formed by acquiring values indicating amounts or states of a plurality of biological materials for each biological material at a plurality of time points is prepared, the plurality of biological materials are divided into a plurality of groups on the basis of temporal variations of time-series data of the respective biological materials, representative time-series data indicating a state of each group is generated on the basis of time-series data of at least one biological material included in each group, and dependencies between the groups are estimated on the basis of the representative time-series data of each group.
Claims12
A biological material analysis support-system comprising a biological material analysis device having a storage device, an input device, and a display device, wherein the biological material analysis device is configured to execute a process comprising:
- preparing time-series data formed by acquiring, from a user via the input device or from the storage device, values indicating amounts or states of a plurality of biological materials for each of the biological materials at a plurality of time points;
- dividing the plurality of biological materials into a plurality of groups on the basis of a temporal variation of the time-series data of each of the biological materials;
- generating representative time-series data indicating a state of each group through computation on the basis of the time-series data of at least one biological material included in each group;
- estimating a dependency between the groups through computation on the basis of the representative time-series data of each group;
- generating a network diagram in which the respective groups are expressed as nodes and nodes corresponding to groups having the dependency are connected through edges,
- displaying the network diagram to the user via the display device;
- receiving selection of the node included in the network diagram from the user via the input device;
- and
- additionally displaying character information or a diagram relating to a biological function of a group corresponding to the selected node, a diagram indicating a name, a sign, a structure or a composition of a biological material included in the group corresponding to the selected node, or character information relating to the biological material in the network diagram,
- wherein the plurality of biological materials are divided into a plurality of groups on the basis of a similarity of temporal variations of time-series data of the respective biological materials and a similarity of biological functions of the respective biological materials,
- wherein in a case where the plurality of biological materials are divided into the plurality of groups, at least one biological material is allowed to belong to a plurality of groups, and
- wherein in a case where the dependency between the groups is estimated, representative time-series data of each group is expressed as a function of representative time-series data of another group.
9 more elements
A biological material analysis system comprising:
- a biological material analysis device comprising:
- an input device;
- a storage device that stores time-series data formed by acquiring values, from a user via the input device or from the storage device indicating amounts or states of a plurality of biological materials for each of the biological materials at a plurality of time points;
- a classifier that divides the plurality of biological materials into a plurality of groups on the basis of a temporal variation of time-series data of each of the biological materials;
- a dependency estimator that generates representative time-series data indicating the state of each group on the basis of time-series data of at least one biological material included in each group, and estimates a dependency between the groups on the basis of the representative time-series data of each group;
- a controller generating a network diagram in which the respective groups are expressed as nodes and nodes corresponding to groups having the dependency are connected through edges, and
- a display device that displays the network diagram to the user via the display device,
- wherein the input device receives, from the user, selection of the node included in the network diagram;
- wherein the display device additionally displays character information or a diagram relating to a biological function of a group corresponding to the selected node, a diagram indicating a name, a sign, a structure or a composition of a biological material included in the group corresponding to the selected node, or character information relating to the biological material in the network diagram,
- wherein the plurality of biological materials are divided into a plurality of groups on the basis of a similarity of temporal variations of time-series data of the respective biological materials and a similarity of biological functions of the respective biological materials,
- wherein in a case where the plurality of biological materials are divided into the plurality of groups, at least one biological material is allowed to belong to a plurality of groups, and
- wherein in a case where the dependency between the groups is estimated, representative time-series data of each group is expressed as a function of representative time-series data of another group.
9 more elements
A non-transitory computer-readable storage medium storing a biological material analysis program for causing a computer in a biological material analysis system comprising a biological material analysis device having the computer, a storage device, an input device, and a display device, to execute:
- a step of storing time-series data formed by acquiring values, from a user via the input device or from the storage device, indicating amounts or states of a plurality of biological materials for each of the biological materials at a plurality of time points;
- a step of dividing the plurality of biological materials into a plurality of groups on the basis of a temporal variation of the time-series data of each of the biological materials;
- a step of generating representative time-series data indicating a state of each group on the basis of the time-series data of at least one biological material included in each group, and estimating a dependency between the groups on the basis of the representative time-series data of each group;
- a step of generating a network diagram in which the respective groups are expressed as nodes and nodes corresponding to groups having the dependency are connected through edges,
- a step of displaying the network diagram to the user via the display device,
- a step of receiving selection of the node included in the network diagram from the user via the input device;
- and
- a step of additionally displaying character information or a diagram relating to a biological function of a group corresponding to the selected node, a diagram indicating a name, a sign, a structure or a composition of a biological material included in the group corresponding to the selected node, or character information relating to the biological material in the network diagram,
- wherein the plurality of biological materials are divided into a plurality of groups on the basis of a similarity of temporal variations of time-series data of the respective biological materials and a similarity of biological functions of the respective biological materials,
- wherein in a case where the plurality of biological materials are divided into the plurality of groups, at least one biological material is allowed to belong to a plurality of groups, and
- wherein in a case where the dependency between the groups is estimated, representative time-series data of each group is expressed as a function of representative time-series data of another group.
8 more elements
Dependencies are inferred from the claim text.