Method and device for generating a three-dimensional synthetic image from a three-dimensional input image

A device for generating at least a three-dimensional synthetic image from a three-dimensional input image, the device comprising a control unit configured to:

• receive a three-dimensional input image representing a part of a body of a subject, said part comprising a bone portion,
• convert the three-dimensional input image into a first vector that presents dimensions lower than dimensions of the three-dimensional input image,
• determine, using a diffusion module, a modified vector by applying a diffusion processing to the first vector, the modified vector corresponding to a noisy representation of the first vector, said diffusion module being configured to receive, as input, the first vector and to provide, as output, the modified vector,
• determine, using a reverse diffusion module, a second vector by applying a reverse diffusion processing to the modified vector, the second vector corresponding to a denoised representation of the modified vector, said reverse diffusion module being configured to receive, as input, the modified vector and to provide, as output, the second vector, and
• convert the second vector into a three-dimensional synthetic image that presents the same dimensions as the three-dimensional input image, the three-dimensional synthetic image representing said part of the body of the subject, said part comprising the bone portion.