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US 12,584,920 B2Granted
Method of detecting cancer or cancer cells
AssigneePanka Cancer Research AG
InventorsKlaus Pantel, Kai Bartkowiak
Life of this patent
Estimating the term…
Abstract
The present invention provides methods of detecting breast cancer or breast cancer cells comprising: (a) obtaining a liquid sample from a subject which sample comprises cells, microvesicles and/or exosomes; and (b) determining the presence of soluble or cell surface associated Cyr61 in the sample; wherein the liquid sample is selected from blood, and/or bone marrow aspirate and wherein the determination of the presence of Cyr61 comprises detection via ELISA.
Claims14
Method of detecting breast cancer or breast cancer cells from a liquid biopsy and treating a subject, said method comprising:
- (a) detecting in a liquid sample comprising cells obtained from the subject the presence of circulating tumor cells and/or disseminating tumor cells and the presence of cell surface associated Cyr61 in the liquid sample by ELISA, immunocytochemistry, or mass spectrometry;
- and
- (b) administering an effective amount of an anti-cancer drug to the subject, wherein the liquid sample is selected from blood, and/or bone marrow aspirate.
Dependencies are inferred from the claim text.