Coating agent for inducing differentiation of pluripotent stem cells into brain microvascular endothelium-like cells and use thereof
AssigneePublic University Corporation Nagoya City University
InventorsTamihide Matsunaga, Tadahiro Hashita, Hiromasa Aoki, Misaki Yamashita
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Abstract
Provided is a technology allowing for stable supply of brain microvascular endothelium-like cells. This coating agent for inducing differentiation of pluripotent stem cells into brain microvascular endothelium-like cells contains at least one component of a Laminin-221 fragment or an N-terminal Vitronectin.
Claims4
A method of producing brain microvascular endothelium cells by inducing differentiation of pluripotent stem cells, comprising a step of culturing the pluripotent stem cells on a culture surface that is coated with at least a Laminin-221 fragment.
Dependencies are inferred from the claim text.