Acoustic separation of a test sample

A method comprising:

• determining a value based on a hematocrit of a test sample comprised of plasma and red blood cells;
• applying acoustic waves to a fluidic channel containing the test sample to separate the plasma from the red blood cells, at least one of an amplitude, a frequency, or a duration of the acoustic waves applied to the fluidic channel being based on the value;
• performing optical detection on the plasma;
• determining hemolysis of the test sample based on a result of the optical detection;
• wherein memory stores a look-up table (LUT), the LUT storing:
• multiple voltages, each voltage corresponding to an amplitude of acoustic waves for a specified value;
• multiple frequencies, each frequency corresponding to a frequency of acoustic waves for a specified value;
• and
• multiple durations, each duration corresponding to a duration of acoustic waves to be applied for a specified value;
• and
• wherein applying the acoustic waves is controlled by a control system, the control system controlling applying the acoustic waves by performing operations comprising:
• selecting a voltage from the LUT based on the value;
• selecting a frequency from the LUT based on the value;
• selecting a duration from the LUT based on the value;
• and
• controlling applying the acoustic waves based on the voltage selected, the frequency selected, and the duration selected.

A system comprising:

• a detector configured to detect a value that is based on a hematocrit of a test sample comprised of plasma and red blood cells;
• a fluidic channel configured to hold the test sample;
• an acoustic transducer configured to apply acoustic waves to the fluidic channel to separate the plasma from the red blood cells in the fluidic channel;
• a control system configured to control the acoustic transducer to produce acoustic waves that sweep over a range of frequencies, the range of frequencies being based on the value;
• and
• memory storing a look-up table (LUT), the LUT storing:
• multiple voltages, each voltage corresponding to an amplitude of acoustic waves for a specified value;
• multiple ranges of frequencies, each range of frequency corresponding to a range of frequency of acoustic waves for a specified value;
• and
• multiple durations, each duration corresponding to a duration of acoustic waves to be applied for a specified value;
• wherein the control system is configured to control the acoustic transducer by performing operations comprising:
• selecting a voltage from the LUT based on the value;
• selecting a range of frequencies from the LUT based on the value;
• selecting a duration from the LUT based on the value;
• and
• controlling the acoustic transducer based on the voltage selected, the range of frequencies selected, and the duration selected.