Extracellular vesicles from microalgae
AssigneesConsiglio Nazionale Delle Richerche, Atlantic Technological University
InventorsAntonella Bongiovanni, Mauro Manno, Gabriella Pocsfalvi, Nicolas Touzet
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Abstract
Extracellular vesicles derived from native, photosynthetic, non-fermenting microalgae are provided. A method for isolating extracellular vesicles from native, photosynthetic, non-fermenting microalgae involving growth, centrifugation and ultracentrifugation steps is also provided. Use of the isolated extracellular vesicles as carriers for delivering diagnostic, therapeutic, nutraceutic and/or cosmetic agents is further provided.
Claims4
An extracellular vesicle (EV) derived from a microalga, wherein the extracellular vesicle (EV) is a biogenic lipidic membranous nanovesicle having a particle size ranging from 50 to 300 nm, being a small extracellular vesicle (sEV) or from 300 nm to 2 μm, being a large extracellular vesicle (lEV) and comprises a lipidic bilayer membrane, and wherein the extracellular vesicle (EV) is derived from a native, photosynthetic, non-fermenting microalga and contains at least the extracellular vesicle protein marker Alix and one or more protein markers selected from the group consisting of enolase, actin and any combination thereof.
Dependencies are inferred from the claim text.