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US 12,583,936 B2Granted
Subcutaneous formulations of anti-CD38 antibodies and their uses
AssigneeJanssen Biotech, Inc.
InventorsRichard Jansson, Vineet Kumar
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Abstract
The present invention relates to subcutaneous formulations of anti-CD38 antibodies and their uses.
Claims30
A pharmaceutical composition comprising:
- a) daratumumab at a concentration of about 120 mg/mL, and
- b) rHuPH20 recombinant hyaluronidase,
- wherein the pharmaceutical composition:
- is a solution suitable for subcutaneous administration,
- has a total volume of about 15 mL, and
- has a hyaluronidase enzymatic activity of about 2000 U/mL.
3 more elements
Dependencies are inferred from the claim text.