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US 12,583,908 B2Granted
Albumin protein variants, production thereof and uses of same
AssigneeYeda Research and Development Co. Ltd.
InventorsSarel Fleishman, Olga Khersonsky
Life of this patent
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Abstract
An albumin protein is provided. The albumin protein is soluble when expressed in bacteria and characterized by increased thermostability as compared to wild type human serum albumin (HSA). Also provided are nucleic acid molecules encoding the albumin protein, compositions comprising the albumin protein and uses thereof.
Claims7
An albumin protein variant comprising:
- the amino acid sequence set forth in SEQ ID NO:
- 3, 5 or 7;
- and
- wherein the albumin protein variant is soluble when expressed in bacteria and characterized by increased thermostability as compared to wild type human serum albumin (HSA) of SEQ ID NO:
- 1.
2 more elements
Dependencies are inferred from the claim text.