Construction of chimeric antigen receptor targeting CD20 antigen and activity identification of engineered T cells thereof

A vector comprising a nucleic acid which encodes a chimeric antigen receptor (CAR), wherein the CAR comprises an amino acid sequence set forth in SEQ ID NO:

• 5.

A pharmaceutical composition comprising a vector, wherein the vector comprises a nucleic acid encoding a chimeric antigen receptor (CAR), and wherein the CAR comprises an amino acid sequence set forth in SEQ ID NO:

• 5.

An immune cell comprising a nucleic acid which encodes a chimeric antigen receptor (CAR), wherein the CAR comprises an amino acid sequence set forth in SEQ ID NO:

• 5.

A pharmaceutical composition comprising an immune cell, wherein the immune cell comprises a nucleic acid encoding a chimeric antigen receptor (CAR), and wherein the CAR comprises an amino acid sequence set forth in SEQ ID NO:

• 5.

A nucleic acid, comprising a nucleic acid sequence set forth in SEQ ID NO:

• 6.

A vector comprising a nucleic acid, wherein the nucleic acid comprises a nucleic acid sequence set forth in SEQ ID NO:

• 6.

A pharmaceutical composition comprising a vector, wherein the vector comprises a nucleic acid, and wherein the nucleic acid comprises a nucleic acid sequence set forth in SEQ ID NO:

• 6.

An immune cell comprising a nucleic acid, wherein the nucleic acid comprises a nucleic acid sequence set forth in SEQ ID NO:

• 6.

A pharmaceutical composition comprising an immune cell, wherein the immune cell comprises a nucleic acid, and wherein the nucleic acid comprises a nucleic acid sequence set forth in SEQ ID NO:

• 6.