Synthetically modifiable ion channels

An ordered functional nanoporous material (OFNM) composition having at least one nanopore comprising:

• wherein:
• X is N or CH;
• dashed bonds (---) indicate that the bond is a single bond or a double bond;
• each R is independently H, Cl, Br, I, C4H4S, SO3H, CO2H, C≡CH, CH═CH2, NH3, OH, C≡N, C1-C4 alkyl, (CH2)xCH═CH2, or (CH2)yCH═CH(CH2)z where x or (y+z) is an integer of 0 to 4 inclusive, (CH2)jCH≡CH, or (CH2)kCH≡C(CH2)r where j or (k+r) is an integer of 0 to 4 inclusive, an aromatic, a heteroaromatic, an amino acid, a glycol, a sugar, a dipeptide, a tripeptide, an oligopeptide, a protein, a nucleic acid, a virus, or a substituted form of any of the aforementioned in which an aliphatic or aromatic hydrogen is replaced with a substituent of a halide, SH, primary amine, secondary amine, tertiary amine, OH, CO2H, SO3H, or C2-C4 alkenyl;
• and
• partial bonds () are completed by joining to complementary portions of other nanopores or are a terminal substituent comprising NH2 or O.