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US 12,582,984 B1Granted
Method for lyophilization and device thereof
AssigneeArgonaut Manufacturing Services, Inc.
InventorMark Nowakowski
Life of this patent
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Abstract
The present disclosure provides a method of generating lyophilized reagents in a multiwell substrate.
Claims11
A method of producing a multiwell substrate having a lyophilized reagents in a multiwell substrate comprising:
- a) providing a multiwell substrate having a plurality of wells formed therein, wherein each of the plurality of wells has a surface in the well;
- b) treating the surface in each of the plurality of wells with an oxygen plasma treatment to render the surface in each of the plurality of wells hydrophilic;
- c) depositing a liquid reagent in each of the plurality of wells;
- and
- d) lyophilizing the liquid reagent in each of the plurality of wells, thereby freezing the liquid reagent below its melting point and reducing pressure to form a lyophilized reagent in the form of a disc within each of the plurality of wells of the multiwell substrate.
2 more elements
Dependencies are inferred from the claim text.