Method for manufacturing a biological analysis chip and biological analysis chip
AssigneePreciphos
InventorsPascal Pflimlin, Bernard Ludwig
Life of this patent
Estimating the term…
Abstract
Disclosed is a method for manufacturing an analysis chip for analysing a biological sample (1), which method comprises providing two support matrices (10), in each of which at least one through hole has been formed (11); providing at least one sheet (13) of solid and porous analysis material; superposing, in the following order, a (lower) support matrix (10a), the sheet (6) of analysis material and an (upper) support matrix (10b); mechanically assembling the two support matrices (10) and the sheet (13) of analysis material, during which a pressing force is applied at right angles to the lower and upper surfaces of the support matrices (10) so as to bring the support matrices (10) closer to each other.
Claims13
A method of manufacturing a biological sample analysis chip comprising:
- an upper support matrix made of a solid support material, the upper support matrix having, an upper support matrix upper surface, an upper support matrix lower surface and at least one upper support matrix through hole;
- a lower support matrix made of the solid support material, the lower support matrix having a lower support matrix upper surface, a lower support matrix upper surface and at least one lower support matrix through hole wherein the lower support matrix upper surface faces the upper support matrix lower surface, each lower support through hole of the at least one lower support matrix through hole aligns with a corresponding upper support through hole of the at least one upper support matrix through hole;
- a first sheet made of a first porous solid analysis material, the first sheet having a first sheet upper surface and a first sheet lower surface;
- a second sheet made of a second porous solid analysis material different from the first porous solid analysis material, the second sheet having a second sheet upper surface and a second sheet lower surface wherein the first sheet and the second sheet are disposed between the upper support matrix and the lower support matrix;
- the method comprising:
- assembling a mechanical assembly including the lower support matrix, the upper support matrix, the first sheet and the second sheet wherein the lower support matrix upper surface faces the upper support matrix lower surface and each through hole of the at least one lower support matrix through hole aligns with the corresponding through hole of the at least one upper support matrix through hole;
- intercalating the first sheet and the second sheet between the upper support matrix and the lower support matrix;
- and
- approximating the upper support matrix and lower support matrix by exerting a pressing force in a direction normal to the support matrix lower surface and the support matrix upper surface thereby providing the biological sample analysis chip.
A biological sample analysis chip biological sample analysis chip for diagnosing a condition and for performing an immunological test comprising:
- an upper support matrix made of a solid support material, the upper support matrix having, an upper support matrix upper surface, an upper support matrix lower surface and at least one upper support matrix through hole;
- a lower support matrix made of the solid support material, the lower support matrix having a lower support matrix upper surface, a lower support matrix upper surface and at least one lower support matrix through hole wherein the lower support matrix upper surface faces the upper support matrix lower surface, each lower support through hole of the at least one lower support matrix through hole aligns with a corresponding upper support through hole of the at least one upper support matrix through hole;
- a first sheet made of a first porous solid analysis material, the first sheet having a first sheet upper surface and a first sheet lower surface;
- a second sheet made of a second porous solid analysis material different from the first porous solid analysis material, the second sheet having a second sheet upper surface and a second sheet lower surface wherein the first sheet and the second sheet are disposed between the upper support matrix and the lower support matrix.
Dependencies are inferred from the claim text.