Bronchial denervation using integrated A-mode signal for optimization of ultrasound treatment

System for conducting pulmonary treatment in a mammalian subject, comprising:

• an elongated member having a balloon, cooling fluid within the balloon, and an energy transducer, the transducer adapted for insertion into a bronchial branch of a bronchial tree of the mammalian subject and configured for transmitting energy into surrounding tissue, and
• a control electrically connected to the transducer, the control adapted to control the transducer to emit ultrasound energy into an impact volume encompassing the bronchial branch so that the energy is applied at a therapeutic level sufficient to inactivate conduction of bronchial nerves throughout the impact volume;
• a pressure sensor configured to monitor fluid flow to determine a diameter of the bronchial branch based on detection of pressure increase of the balloon in relation to fluid volume increase.