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US 12,582,818 B2Granted
System and method for scaling orthopedic implant stimulation
AssigneeIntelligent Implants Limited
InventorsErik Robert Zellmer, John Zellmer
Life of this patent
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Abstract
A system and method for spinal fusion that can include: a spinal cage body that includes at least one defined graft window cavity; a plurality of electrodes exposed on the surface of the spinal cage body; control circuitry configured to drive the plurality of electrodes in a stimulation mode; wherein there is at least a targeted osteoinduction region and a targeted non-osteoinduction region that are immediately adjacent to the spinal cage body; and wherein the control circuitry includes configuration to excite the plurality of electrodes during the stimulation mode for generation of a current density in the targeted osteoinduction region and targeted non-osteoinduction region according to targeted levels of bone growth.
Claims14
A system for spinal fusion comprising:
- a spinal cage body that includes at least one defined graft window cavity;
- a plurality of electrodes exposed on the surface of the spinal cage body;
- control circuitry configured to drive the plurality of electrodes in a stimulation mode;
- wherein there is at least a targeted osteoinduction region and a targeted non-osteoinduction region that are immediately adjacent to the spinal cage body;
- wherein the control circuitry includes configuration to excite the plurality of electrodes during the stimulation mode for generation of a current density in the targeted osteoinduction region and targeted non-osteoinduction region according to targeted levels of bone growth;
- and
- wherein the control circuitry includes further configuration of an impedance mode, wherein impedance measurements can be made between at least two electrodes of the plurality of electrodes to form an impedance dataset, and wherein control circuitry is further configured to trigger a response based on comparison of the impedance dataset and the targeted levels of bone growth, wherein configuration to trigger the response based on comparison of the impedance dataset and targeted levels of bone growth comprises configuration to detect a bone formation state when impedance measurements in the targeted osteoinduction region reaches 1.2-1.5 kΩ and detect a non-bone tissue state when the impedance measurement in the targeted non-osteoinduction region is less than 0.6-0.8 kΩ.
4 more elements
A system for spinal fusion comprising:
- a spinal cage body that includes at least one defined graft window cavity;
- a plurality of electrodes exposed on the surface of the spinal cage body;
- control circuitry configured to drive the plurality of electrodes in a stimulation mode;
- wherein there is at least a targeted osteoinduction region and a targeted non-osteoinduction region that are immediately adjacent to the spinal cage body;
- wherein the control circuitry includes configuration to excite the plurality of electrodes during the stimulation mode for generation of a current density in the targeted osteoinduction region and targeted non-osteoinduction region according to targeted levels of bone growth;
- wherein the plurality of electrodes comprises a set of cathode electrodes configured in connection with the control circuitry for excitation as cathodes, wherein the set of cathode electrodes are positioned on the spinal cage body based on position of the targeted osteoinduction region relative to the spinal cage body;
- wherein the targeted osteoinduction region is adjacent to a subregion of an external wall;
- and
- wherein the spinal cage body comprises a defined side through-hole with one end within the subregion of the external wall and a second end within an internal wall defining the graft window cavity.
6 more elements
A method comprising:
- providing a spinal cage implant that includes a spinal cage body with a defined graft window, a plurality of electrodes;
- setting a stimulation profile, wherein an osteoinduction region is defined relative to the spinal cage body and a non-osteoinduction region is defined relative to the spinal cage body, wherein the osteoinduction region includes the defined graft window cavity;
- stimulating the plurality of electrodes during a stimulation mode, comprising generating a current density in the osteoinduction region, within one millimeter of a defined endplate surface of the spinal cage body, an average current density between 1.8-9.1 μA/cm2 and a current density in the non-osteoinduction region below 1.8 μA/cm2;
- and
- monitoring impedance measurements between at least two electrodes to form an impedance dataset and triggering a response based on comparison of the impedance dataset and targeted levels of bone growth, comprising detecting a bone formation state when impedance measurements in the osteoinduction region reaches 1.2-1.5 kΩ and detecting a non-bone tissue state when impedance measurements in the non-osteoinduction region is less than 0.6-0.8 kΩ.
2 more elements
Dependencies are inferred from the claim text.