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US 12,582,784 B2Granted
Dry powder inhalation system
AssigneeMannKind Corporation
InventorsChad C. Smutney, P. Spencer Kinsey, John M. Polidoro, Carl R. Sahi, Benoit Adamo, Scott McLean, Dennis Overfield, Anthony Bryant
Life of this patent
Estimating the term…
Abstract
Dry powder inhaler systems for pulmonary delivery of pharmaceuticals are disclosed.
Claims17
A method of treating hyperglycemia, the method comprising:
- administering an inhalable dry powder composition comprising a diketopiperazine having the formula 2, 5-diketo-3,6-di(4-X-aminobutyl)piperazine, wherein X is selected from the group consisting of succinyl, glutaryl, maleyl, and fumaryl, via an inhalation system for pulmonary delivery, said inhalation system comprising a housing and a mouthpiece, said housing including an inlet and an outlet port, and said mouthpiece configured to move translationally within said housing;
- and wherein the inhalation system is configured to be separable into two principal component parts, and wherein said inhalation system provides an airflow resistance ranging from 0.08 and 0.15 ΠkPa/liters per minute.
Dependencies are inferred from the claim text.