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US 12,582,772 B2Granted
LQG artificial pancreas control system and related method
AssigneeUniveristy of Virginia Patent Foundation
InventorsStephen D. Patek, Marc D. Breton
Life of this patent
Estimating the term…
Abstract
The invention relates to a methods and systems for determining an insulin dosing recommendation. The invention employs Linear Quadratic methodology to determine the insulin dosing recommendation based on a patient's present physiological state, which is estimated by an adaptive filter methodology employing a dynamic model, which utilizes real-time measurements of blood glucose concentration.
Claims14
A computer-implemented method for insulin dosing, the method comprising:
- receiving an estimate of a present physiological state, wherein the estimate is based on a model of the present physiological state, wherein the model is one of a plurality of models, wherein the model has a dimensionality that differs from at least one other model of the plurality of models;
- determining an insulin dosage based on the estimate of the present physiological state and a minimization of cost associated with deviation from an operating point;
- and
- at least one of:
- administering the insulin dosage;
- or
- controlling administration of insulin via an insulin dosage signal based on the insulin dosage.
4 more elements
A system for insulin dosing, the system comprising at least one processor, wherein the at least one processor is operable to:
- receive an estimate of a present physiological state, wherein the estimate is based on a model of the present physiological state, wherein the model is one of a plurality of models, wherein the model of the plurality of models has a dimensionality that differs from at least one other model of the plurality models;
- determine an insulin dosage based on the estimate of the present physiological state and a minimization of cost associated with deviation from an operating point;
- and
- at least one of:
- administer the insulin dosage;
- or
- control administration of insulin via an insulin dosage signal based on the insulin dosage.
4 more elements
Dependencies are inferred from the claim text.